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Photofrin (porfimer sodium) for injection is a photosensitizing agent used in the photodynamic therapy of tumors. Following reconstitution of the freeze-dried product with 5% Dextrose Injection (USP) or 0.9% Sodium Chloride Injection (USP), it is injected intravenously. This is followed 40-50 hours later by illumination of the tumor with laser light (630 nm wavelength). Photofrin is not a a single chemical entity; it is a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units. It is a dark red to reddish brown cake or powder. Each vial of Photofrin contains 75 mg of porfimer sodium as a sterile freeze-dried cake or powder. Hydrochloric acid and/or sodium hydroxide may be added during manufacture to adjust pH. There are no preservatives or other additives.
If you have any questions related to coding, coverage and reimbursement for Photofrin, please call the Photofrin Reimbursement Hotline at 1-800-675-8412. Hotline consultants are available to assist you Monday through Friday, from 9am to 8pm Eastern Time.
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©2007, Division of Thoracic Surgery at Brigham and Women's Hospital. All rights reserved.
Division of Thoracic Surgery
Brigham and Women's Hospital
75 Francis Street
Boston, MA 02115
Phone: (617) 732-6824